Search on: SNEDDON SYNDROME 
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Descriptor English:   Sneddon Syndrome 
Descriptor Spanish:   Síndrome de Sneddon 
Descriptor Portuguese:   Síndrome de Sneddon 
Synonyms English:   Sneddon-Champion Syndrome
Livedo Reticularis, Systemic Involvement  
Tree Number:   C10.228.140.300.750
C14.907.253.774
C17.800.862.775
Definition English:   A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of livedo reticularis, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media. (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60) 
Indexing Annotation English:   do not confuse with SNEDDON-WILKINSON DISEASE see SKIN DISEASES, VESICULOBULLOUS
History Note English:   1996 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   32608 
Unique Identifier:   D018860 

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